Movement Disorders [2010] 25 (15) : 2493-2500 (Gallagher DA, Lees AJ, Schrag A.)
Although muscular movement is the most characteristic symptom of Parkinson's Disease, non-motor symptoms (those that do not concern muscular movement) are increasingly recognised as neglected aspects of Parkinson's Disease. The most common non-motor symptom has been found to be urinary. In order of frequency the most common symptoms are : autonomic dysfunction, particularly urinary and gastrointestinal
symptoms (84%), mood (74%), fatigue (74%), daytime somnolence (65%), pain (56%), nocturnal sleep problems (55%), and psychosis (55%). Motor fluctuations (57%) and dyskinesia (43%) were associated with worse quality of life. Depression had the strongest association with a lower health related quality of life, then fatigue, thermoregulatory, gastrointestinal, cardiovascular autonomic function, daytime somnolence, and urinary problems. Whilst psychiatric problems are increasingly documented, many symptoms, particularly those perceived as embarrassing or unrelated, remain under reported.
Although muscular movement is the most characteristic symptom of Parkinson's Disease, non-motor symptoms (those that do not concern muscular movement) are increasingly recognised as neglected aspects of Parkinson's Disease. The most common non-motor symptom has been found to be urinary. In order of frequency the most common symptoms are : autonomic dysfunction, particularly urinary and gastrointestinal
symptoms (84%), mood (74%), fatigue (74%), daytime somnolence (65%), pain (56%), nocturnal sleep problems (55%), and psychosis (55%). Motor fluctuations (57%) and dyskinesia (43%) were associated with worse quality of life. Depression had the strongest association with a lower health related quality of life, then fatigue, thermoregulatory, gastrointestinal, cardiovascular autonomic function, daytime somnolence, and urinary problems. Whilst psychiatric problems are increasingly documented, many symptoms, particularly those perceived as embarrassing or unrelated, remain under reported.
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