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Friday, April 15, 2016

Veterinarian challenges gaps in Parkinson's knowledge, as science remains suspended in 20th century

ABC Rural By Danielle Grandly
April 15, 2016


Science cannot prove Dr David Rendell's lifelong exposure to farm chemicals caused his Parkinson's disease, nor can it provide any reason to dampen his life ambitions.

The veterinarian absorbed this week's national media coverage of a potential connection between chemical exposure and the degenerative disease with a bemused hope.

As a teenager I waved a flag for an aeroplane to spray paddocks with Paraquat [herbicide], and the evidence is quite clear today that Paraquat is definitely linked to an increase chance of Parkinson's.
Dr David Rendell, veterinarian

That was when his left leg started to drag and he lost dexterity in his left hand.
At that stage Dr Rendell had been examining, diagnosing and solving health issues for decades.
He was credited with ground-breaking research and has published dozens of articles in international journals.
But in a cold and confronting meeting, a neurologist handed him a lifelong mystery that will unlikely be solved in the veterinarian's lifetime.
"He wriggled my arm for barely a minute, made a few notes, then looked up and said, 'You've got Parkinson's and there's no doubt about it'," Dr Rendell said.
"He put his head back down again and kept writing."
Links to chemical exposure unproven
A study released this week by Monash University pointed to "a cluster of Parkinson's" in Dr Rendell's region, where sales of Parkinson's medication was up to 78 per cent higher than the average.
Researchers said barley and pulse production was popular in the areas of concern, pointing to a possible connection between chemical use and the disease.
It is unlikely Dr Rendell will ever know the official cause behind his degenerative condition, but the chemical associations are clear enough to raise alarm bells.
"I've certainly been guilty of a cavalier attitude to chemicals," he said.

"As a teenager I waved a flag for an aeroplane to spray paddocks with Paraquat [herbicide], and the evidence is quite clear today that Paraquat is definitely linked to an increased chance of Parkinson's.

"If you give enough of it to mice, they'll get Parkinson's."
Cultural shift in farmers' chemical use
Dr Rendell said farmers' attitudes toward chemicals had changed "dramatically" over the past three decades, but cultural changes needed to continue.
"How many people have drenched a mob of sheep in the last fortnight and put gloves on?" he said.
"We allow ourselves massive contact with these drench chemicals on a daily basis and think nothing of it."
Despite some "cynicism" at the fanfare over this week's dated research findings, Dr Rendell said there was hope the attention would lead to vital research.
Farmer health centre leads early research
Dr Rendell's wife happens to be the founding director of the Hamilton-based National Centre for Farmer Health.

The centre is leading chemical exposure research, by documenting the effects on farmers' nervous systems over 12 months.
Scientists hope it will provide a concrete base for research into the long-term impacts, possibly mapping the observed links between degenerative conditions like Parkinson's and aggressive cancers.
Dr Rendell is also involved in research examining whether exercise can improve the symptoms of Parkinson's.
The 59-year-old is convinced of the benefits, and boasts the title of 'Hamilton park runner of the month' to prove it.
"I've now participated, with my partner Sue, in 19 [runs]," he said.
"I've gone from a shuffler to almost pass myself off as a runner."
Gaps in knowledge liberating
The gaps in knowledge about Parkinson's disease are obviously frustrating for a man of science, but they are also quite liberating.
When neurologists tell Dr Rendell he should stop doing the things he loves, he simply stops seeing them.
His first one lasted a single visit.
"He counselled me strongly about doing any public speaking," Dr Rendell said.
"His view was that it would make me anxious and accelerate the symptoms.
"My view is that there's not much evidence that is correct, and that I enjoy what I do and to hell with his patronising comments."
When the next one expressed "downright cynicism" at Dr Rendell's belief in the benefits of exercise, he went too.
Disease masks an animated life
A first encounter of Dr Rendell reveals nothing of a man suffering a degenerative condition.
His words might be spaced and his leg might jiggle under the desk, but to a stranger he presents as a thoughtful professional.
Only those who know and love him can appreciate the changes.
Animated tales are now told deadpan. An outspoken personality has been reined in.
"I guess it's caused me to pause and think a bit ... and I think it's taken some of the sharp edges off my personality," he said.
"There has been some benefits, but hey, I'd prefer the prickly David Rendell without Parkinson's."
Renowned in his field, Dr Rendell continues to travel across Australia presenting research findings and advising peers.
On most days the new grandfather can be found in a paddock, arm-deep in the midst of impregnating cattle, performing autopsies or testing for diseases.
Nearly a decade on from his diagnosis, he still keeps tabs on a list of research sites.
But the obsession for answers has faded.
"I know I'm not going to get better," he said.
"We're all going to go back to dust; I'm determined to travel the journey with dignity and with pride.
"If people can be inspired by that, that's the greatest legacy I could ever leave."


http://health.einnews.com/article/321583364/Gv9lcnBBWEZ1LqKW

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