Dysphagia (difficulty in swallowing) is a common problem in people with Parkinson's
Disease. In order to assess the prevalence of dysphagia and other related symptoms, people
with Parkinson's Disease presenting with dysphagia, odynophagia, heartburn, regurgitation,
chest pain, and weight loss underwent evaluation using high-resolution manometry (HRM).
Most people with Parkinson's Disease (62%) experienced
dysphagia (difficult swallowing), which probably contributed to
weight loss in 41% of people because they were unable to eat as
much. The prevalence of other symptoms was heartburn (37%),
regurgitation (31%), chest pain (28%), and odynophagia (painful
swallowing) (6%). Problems in the esophagus were also
common.
The esophagus is through which food passes from the
mouth to the stomach. The most common problems were : failure
by the esophagus to contract properly (ineffective esophageal
peristalsis) (55%), fragmented contraction in the esophagus
(fragmented peristalsis) (48%), spasms in the esophagus (DES -
diffuse esophageal spasm) (48%), and obstruction of the exit of
the esophagus to the stomach (EGJ outflow obstruction) (39%).
Each of these causes digestive problems.
Reference : Diseases of the Esophagus [2017] 30 (4) : 1-6 (A.Su, R.Gandhy, C.Barlow,
G.Triadafilopoulos) Complete abstract : http://www.ncbi.nlm.nih.gov/pubmed/28375482
http://www.viartis.net/parkinsons.disease/news/170416.pdf
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