In Parkinson's disease (PD) patients, certain MHC alleles have been found to be more prevalent than others. Researchers are now looking into whether PD is associated with an antigen-specific T cell response to α-Synuclein, a hallmark PD protein that aggregates and forms Lewy Bodies. It is now possible for α-Synuclein in the cerebrospinal fluid to be captured by antigen presenting cells and displayed by PD-associated MHC alleles, promoting adaptive immune responses.
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https://www.technologynetworks.com/tn/editors-pics/imaging-parkinsons-disease-292842
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