Our Parkinson's Place
WELCOME TO OUR PARKINSON'S PLACE!
I HAVE PARKINSON'S DISEASES AND THOUGHT IT WOULD BE NICE TO HAVE A PLACE WHERE THE CONTENTS OF UPDATED NEWS IS FOUND IN ONE PLACE. THAT IS WHY I BEGAN THIS BLOG.
I COPY NEWS ARTICLES PERTAINING TO RESEARCH, NEWS AND INFORMATION FOR PARKINSON'S DISEASE, DEMENTIA, THE BRAIN, DEPRESSION AND PARKINSON'S WITH DYSTONIA. I ALSO POST ABOUT FUNDRAISING FOR PARKINSON'S DISEASE AND EVENTS. I TRY TO BE UP-TO-DATE AS POSSIBLE.
I AM NOT RESPONSIBLE FOR IT'S CONTENTS. I AM JUST A COPIER OF INFORMATION SEARCHED ON THE COMPUTER. PLEASE UNDERSTAND THE COPIES ARE JUST THAT, COPIES AND AT TIMES, I AM UNABLE TO ENLARGE THE WORDING OR KEEP IT UNIFORMED AS I WISH. IT IS IMPORTANT TO UNDERSTAND I AM A PERSON WITH PARKINSON'S DISEASE. I HAVE NO MEDICAL EDUCATION,
I JUST WANT TO SHARE WITH YOU WHAT I READ ON THE INTERNET. IT IS UP TO YOU TO DECIDE WHETHER TO READ IT AND TALK IT OVER WITH YOUR DOCTOR. I AM JUST THE COPIER OF DOCUMENTS FROM THE COMPUTER. I DO NOT HAVE PROOF OF FACT OR FICTION OF THE ARTICLE. I ALSO TRY TO PLACE A LINK AT THE BOTTOM OF EACH ARTICLE TO SHOW WHERE I RECEIVED THE INFORMATION SO THAT YOU MAY WANT TO VISIT THEIR SITE.
THIS IS FOR YOU TO READ AND TO ALWAYS KEEP AN OPEN MIND.
PLEASE DISCUSS THIS WITH YOUR DOCTOR, SHOULD YOU HAVE ANY QUESTIONS, OR CONCERNS. NEVER DO ANYTHING WITHOUT TALKING TO YOUR DOCTOR FIRST..
I DO NOT MAKE ANY MONEY FROM THIS WEBSITE. I VOLUNTEER MY TIME TO HELP ALL OF US TO BE INFORMED.
I WILL NOT ACCEPT ANY ADVERTISEMENT OR HEALING POWERS, HEALING FROM HERBS AND ETC. UNLESS IT HAS GONE THROUGH TRIALS AND APPROVED BY FDA. IT WILL GO INTO SPAM.
THIS IS A FREE SITE FOR ALL WITH NO ADVERTISEMENTS
THANK YOU FOR VISITING! TOGETHER WE CAN MAKE A DIFFERENCE!
TRANSLATE
Wednesday, April 26, 2023
Sunday, July 24, 2022
Happenings as of July 2022
July 24, 2022
My health has been like a roller coaster since December 2020. I have fallen several times. Most of the time I am short of breath. It is hard to exercises on those days. I am officially 73 years old.
I had quite an interested evening a few weeks ago. I was almost ready to go to dinner when I began to pick up my foot to put my shoe on, when all of a sudden on the outside near the bottom of my left foot a small vein pop squirting blood everywhere.
We did all of the following:
Elevate your leg above your heart to slow the bleeding. Apply gentle, consistent pressure over the vein. Once bleeding is under control, wrap the vein with a bandage.
We couldn't get the bleeding to stop. My husband called 911. Firemen arrived and it took some time to get the bleeding to stop. They did all of what we did, but wrapped my foot tighter. They instructed me to continue keeping my leg and foot elevated, stating if it begins to bleed again, go to the ER and have them stitch it up. I cancelled the ambulance.
Fortunately it stop bleeding but was quite sore for 3 days. I lost over a cup or more possible close to a pint of blood, my husband said. He cleaned it all up.
The weather here in Southwest Florida has been hot, hot and more hot with the humidity extremely high. This really takes my breath away. So I don't have the energy like I use to.
I am tired more than normal . I have not been able to exercise like I use to.
I am hoping this weather will improve and I will begin to breath better.
I have not given up.
Monday, February 3, 2020
I want to Inform you of what happened to me.
Monday, December 23, 2019
Where is the news?
My first Day in the Hospital ! |
I AM SENDING MY APOLOGIES TO YOU!
I just returned after 14 days from the hospital, including Therapy.
A nurse will evaluate me tomorrow, Christmas eve, to see what kind of therapy is needed to
get me back to the best I can be.
Dec. 23, 2019 |
As soon as I can, I will be back online. Have a very Merry Christmas!
God Bless!
Saturday, December 7, 2019
Understanding What Parkinson’s Progression Means to Each Patient
Dosing Begins in Phase 2 Trial of CNM-Au8, Potential Therapy for Dopaminergic Neurons
Thursday, December 5, 2019
Exploring the Diversity of Parkinson's Proteins
Patent Describes Apple Watch Feature for Improving Treatment of Parkinson's Disease Symptoms
"There are an estimated 600,000 to 1 million cases of Parkinson's Disease in the United States and 60,000 new cases are diagnosed each year," reads the filing, which goes on to describe the symptoms sufferers have to live with. "Symptoms of PD include... tremor and dyskinesia. Dyskinesia is an uncontrollable and involuntary movement that can resemble twitching, fidgeting, swaying or bobbing."
"A patient's quality of life is largely dependent on how precisely clinicians titrate and schedule the patient's medications to minimize the patient's symptoms. This is a challenge for clinicians because each patient has a different combination of symptoms that can change and become more severe over time. Also, in any given day the symptoms may fluctuate based on medications, food intake, sleep, stress, exercise, etc."
Scientists identify chaperones as potential therapies for Parkinson's disease
University of Basel, Biozentrum |
Drug helped dementia patients curb their hallucinations and delusions
(Acadia Pharmaceuticals Inc. via Associated Press)
A drug that curbs delusions in Parkinson’s patients did the same for people with Alzheimer’s disease and other forms of dementia in a clinical trial that was stopped early because the benefit seemed clear.
If regulators agree, the drug could become the first offered specifically for treating dementia-related psychosis. It would also be the first new medicine for Alzheimer’s in nearly two decades.
The daily pill targets some of the most troubling symptoms that patients and caregivers face — hallucinations that often lead to anxiety, aggression, and physical and verbal abuse.
“This would be a very important advance,” said one independent expert, Dr. Howard Fillit, chief science officer of the Alzheimer’s Drug Discovery Foundation.
Although the field is focused on finding a cure for dementia and preventing future cases, “there is a huge unmet need for better treatment” for those who have it now, said Maria Carrillo, chief science officer for the Alzheimer’s Assn.
The drug, pimavanserin, is sold as Nuplazid by Acadia Pharmaceuticals Inc. It was approved for Parkinson’s-related psychosis in 2016 and is thought to work by blocking a brain chemical that seems to spur delusions.
About 8 million Americans have dementia, and studies suggest that up to 30% of them develop psychosis.
“It’s terrifying,” said Dr. Jeffrey Cummings of the Cleveland Clinic Lou Ruvo Center for Brain Health in Las Vegas. “You believe that people might be trying to hurt you. You believe that people are stealing from you. You believe that your spouse is unfaithful to you. Those are the three most common false beliefs.”
Cummings consults for Acadia and helped lead the study, which included about 400 people with dementia and psychosis. All were given a low dose of the drug for three months, and those who seemed to respond or benefit were then split into two groups. Half continued on the drug and the others were given dummy pills for six months or until they had a relapse or worsening of symptoms. Neither the patients nor their doctors knew who was getting what.
Independent monitors stopped the study when they saw that those on dummy pills were more than twice as likely as those on the drug to relapse or worsen — 28% versus nearly 13%.
There were relatively few serious side effects — 5% in the drug group and 4% in the others. Headaches and urinary tract infections were more common among those on the drug. Two deaths occurred, but study leaders said neither was related to the drug.
Carrillo said the study was small, but the drug’s effect seemed large. It’s unclear whether the federal Food and Drug Administration would want more evidence to approve a new use.
Current anti-psychotic medicines have some major drawbacks and are not approved for dementia patients.
“They’re often used off-label because we have very few other options,” Fillit said.
All carry warnings that they can raise the risk of death in elderly patients, as does Nuplazid.
The drug costs about $3,000 a month, so cost could be an issue. The amount patients pay can vary depending on insurance coverage.
https://www.latimes.com/science/story/2019-12-05/drug-can-curb-dementia-delusions
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