Mitsubishi Tanabe Pharma America (OTCPK:MTZPY -1.5%) initiates a Phase 3 clinical trial, BouNDless, evaluating continuous subcutaneously administered carbidopa/levodopa (ND0612) compared to the oral formulation in Parkinson's disease (PD) patients.
The study will enroll ~300 PD sufferers who are experiencing motor fluctuations ("OFF" time at least two hours each day) that are no longer adequately controlled by conventional therapies.
The primary endpoint is the change from baseline at week 12 in daily "ON" time without troublesome dyskinesia (uncontrolled movement). The estimated primary completion date is September 2020.
The study design will be presented at the International Congress of Parkinson's Disease and Movement Disorders in Nice, France, September 22-26.
Subsidiary NeuroDerm is leading clinical development.
PD-related tickers: Seelos Therapeutics (SEEL -2.6%), Kyowa Kirin (OTCPK:KYKOF+2.3%), ProMIS Neurosciences (OTCQB:ARFXF), Cerecor (CERC +5%), Voyager Therapeutics (VYGR +2.2%), Anavex Life Sciences (AVXL +0.8%), Adamas Pharmaceuticals (ADMS -0.2%), Axovant Gene Therapies (AXGT +2.5%), Acorda Therapeutics (ACOR +1.5%), Newron Pharmaceuticals S.p.A. (OTCPK:NWPHF), Merck (MRK +0.2%), Bristol-Myers Squibb (BMY +0.4%)
https://seekingalpha.com/news/3495277-mitsubishi-tanabe-launches-late-stage-study-u-s-continuous-parkinsons-therapy
i was diagnosed of parkinson disease 5 years ago,i started azilect,then mirapex as the disease progressed in february last year,and i started on parkinson disease herbal medicine from ultimate life clinic,few months into the treatment i made a significant recovery,almost all my symptoms are gone,great improvement with my movement and balance,it been a year and life has been so good for me,reach them through there website at www.ultimatelifeclinic.com
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