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I COPY NEWS ARTICLES PERTAINING TO RESEARCH, NEWS AND INFORMATION FOR PARKINSON'S DISEASE, DEMENTIA, THE BRAIN, DEPRESSION AND PARKINSON'S WITH DYSTONIA. I ALSO POST ABOUT FUNDRAISING FOR PARKINSON'S DISEASE AND EVENTS. I TRY TO BE UP-TO-DATE AS POSSIBLE.

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Thursday, April 2, 2015

Skin Test May Shed New Light on Alzheimer’s and Parkinson’s Disease

April 2, 2015 9:00

New research has determined that a simple skin biopsy may be able to detect physical indicators of both Parkinson’s and Alzheimer’s disease. Researchers from the University of San Luis Patosi in San Luis, Mexico are presenting their study at the American Academy of Neurology’s 67th Annual Meeting. Using skin biopsies from both healthy individuals and those with various neurological diseases, researchers found that those with Parkinson’s possessed seven times the typical amount of tau proteins while those with Alzheimer’s presented eight times the usual amount of alpha-synuclein protein. “More research is needed to confirm these results, but the findings are exciting because we could potentially begin to use skin biopsies from living patients to study and learn more about these diseases. This also means tissue will be much more readily available for scientists to study,” said the lead researcher of the study. “This procedure could be used to study not only Alzheimer’s and Parkinson’s, but also other neurodegenerative diseases.” To learn more about this study:

Skin Test May Shed New Light on Alzheimer’s and Parkinson’s Diseases

Released: 12-Feb-2015 10:20 AM EST CitationsAAN Annual Meeting, April 2015

Newswise — WASHINGTON, D.C. –

Scientists have discovered a skin test that may shed new light on Alzheimer’s and Parkinson’s diseases, according to a study released today will be presented at the American Academy of Neurology’s 67th Annual Meeting in Washington, D.C., April 18 to 25, 2015.

The study showed that skin biopsies can be used to detect elevated levels of abnormal proteins found in the two diseases.

“Until now, pathological confirmation was not possible without a brain biopsy, so these diseases often go unrecognized until after the disease has progressed,” said study author Ildefonso Rodriguez-Leyva, MD, at Central Hospital at the University of San Luis Potosi in San Luis Potosi, Mexico. “We hypothesized that since skin has the same origin as brain tissue while in the embryo that they might also show the same abnormal proteins. This new test offers a potential biomarker that may allow doctors to identify and diagnose these diseases earlier on.”

For the study, researchers took skin biopsies from 20 people with Alzheimer’s disease, 16 with Parkinson’s disease and 17 with dementia caused by other conditions and compared them to 12 healthy people in the same age group. They tested these skin samples to see if specific types of altered proteins were found—ones that indicate a person has Alzheimer’s or Parkinson’s.

As compared to healthy patients and ones with dementia caused by other conditions, those with both Alzheimer’s and Parkinson’s had seven times higher levels of the tau protein. People with Parkinson’s also had an eight times higher level of alpha-synuclein protein than the healthy control group.

Alzheimer’s disease is ranked as the sixth leading cause of death in the United States, and 5.4 million Americans are currently diagnosed with Alzheimer’s disease. Parkinson’s disease affects one million Americans, with at least 60,000 new cases reported annually each year.

“More research is needed to confirm these results, but the findings are exciting because we could potentially begin to use skin biopsies from living patients to study and learn more about these diseases. This also means tissue will be much more readily available for scientists to study,” said Rodriguez-Leyva. “This procedure could be used to study not only Alzheimer’s and Parkinson’s, but also other neurodegenerative diseases.”

The study was supported by the National Council of Science and Technology of Mexico.

Learn more about Alzheimer’s and Parkinson’s diseases at www.aan.com/patients.

The American Academy of Neurology, an association of more than 28,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer’s disease, stroke, migraine, multiple sclerosis, brain injury, Parkinson’s disease and epilepsy

http://www.aansneurosurgeon.org/2015/04/02/skin-test-may-shed-new-light-on-alzheimers-and-parkinsons-disease/