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I copy news articles pertaining to research, news and information for Parkinson's disease, Dementia, the Brain, Depression and Parkinson's with Dystonia. I also post about Fundraising for Parkinson's disease and events. I try to be up-to-date as possible. I have Parkinson's diseases as well and thought it would be nice to have a place where updated news is in one place. That is why I began this blog.
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Sunday, April 22, 2018
By Joe Elias April 22, 2018
Author: Jaime Berg April 22, 2018
Of the one million Americans living with Parkinson’s disease, 17,000 of them live here in Colorado.
Parkinson’s is a progressive neurological disease that robs individuals of control over their movements.
Exercise has been suggested by doctors as a way to help curb tremors.
Nancy Ivankoe was diagnosed with Parkinson’s five years ago.
“I immediately got educated on how to live in the best condition I can,” Ivankoe said. “What I learned is that exercise is the number one medication for Parkinson’s.”
Ivankoe attends a fitness class at Fit36 in Highlands Ranch twice a week for two reasons:
“One is to see my friends, and two is to increase my fitness,” Ivankoe said.
For her, the classes are more than just a workout; it’s a place to bond and cope with other Parkinson’s patients. She was already into fitness before she was diagnosed, and says if anything changed, it’s the way she works out.
“Research has proven actually that exercises are neuroprotective, meaning it kind of protects our nerve cells from degeneration and it really slows down the progression of the disease,” Ivankoe said.
Ivankoe says she finds that exercise not only helps curb the disease, but it helps mitigate her symptoms.
“I will say that if I didn’t have Parkinson’s, I probably wouldn’t exercise on days I didn’t feel that great, but we with Parkinson’s knew that it is those days in particular that we need to get out to the gym and just do what you can.”
At Fit36, the class focuses on high-intensity training with several different stations. Each station works a part or part of the body and focuses on improving core strength and balance.
According to the Parkinson’s Association of the Rockies, (https://www.parkinsonrockies.org)
there are 47 monthly support groups, and more than 10,000 exercise classes throughout the year.
Studying acrolein in rats
Blocking acrolein slows down Parkinson's
Acrolein is a novel therapeutic target, so this is the first time it's been shown in an animal model that if you lower the acrolein level, you can actually slow the progression of the disease [...]."
Friday, April 20, 2018
18 Apr 2018
B. Subtilis Squelch Synuclein.
Some people around the world already consume . For example, a Japanese breakfast food called natto is made by fermenting soybeans using the probiotic. The Japanese credit consumption of this food as one reason for their longevity. Grau told Alzforum that natto helped inspire his studies of health benefits.
The strain that makes natto produces the protease nattokinase, which degrades amyloid in mice and promotes non-amyloidogenic processing of Aβ (; ). It is unclear if the food affects PD or Alzheimer’s risk. The incidence of Parkinson’s disease in Japan is somewhat lower than in most Western countries ().
Schlossmacher called Grau’s work elegant, with fascinating implications. He noted that probiotics might trigger shifts in the relative abundance of other species in the gut microbiome, leading to changes throughout the intestine. In theory, such microbiome changes could also help prevent PD by keeping the α-synuclein response to infection in check, he said. Signs of ongoing α-synuclein aggregation occur in healthy people in the GI tract, notably in the appendix (), and chronic constipation is associated with PD risk. Gut motility, which is influenced in part by the GI tract’s microbiome constituents, could thus be a modifiable risk factor, Schlossmacher argues.—Madolyn Bowman Rogers
April 20, 2018
This drama about a mother who has Parkinson’s and her teenage son who is struggling with his sexuality, is unsatisfying despite heartfelt moments
Conflicted … Jamie (Théodore Pellerin), who plays Shirley Henderson’s son in Never Steady, Never Still.
This is a sincerely intended drama from Canadian writer-director Kathleen Hepburn, and it was a prizewinner on its home turf, but I have to admit to finding it tough sledding. It is plaintive and subdued, with a dual narrative focus that is not as satisfyingly developed or resolved as it might be.
Judy, played by Shirley Henderson, lives near the oilfields of Alberta and has Parkinson’s. She has a supportive if withdrawn husband, Ed (Nicholas Campbell), though she seems also to have an emotional connection with her neighbour Lenny (Lorne Cardinal). Judy is worried and protective about her aimless teen son Jamie (Théodore Pellerin) who, quite aside from worrying about his mother, has his own issues with sexuality and identity, and who occupies half the film’s narrative space. (The feature was developed from an earlier short that was more centred on Jamie.) In the end, I got the feeling I hadn’t quite found out enough about either Jamie or Judy.
The movie comes most alive in Judy’s Parkinson’s therapy group scenes, which have a wit and punch that the rest of the film lacks. There is a terrific exchange in which an older woman fiercely tells the group how annoyed she was when out shopping for socks for her husband, when her wobbly legs would suddenly fail to move at her bidding and she would be stuck making conversation with the town bore.
There are some heartfelt moments, but this is an opaque and frustrating experience.