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I have Parkinson's diseases and thought it would be nice to have a place where the contents of updated news is found in one place. That is why I began this blog.
I copy news articles pertaining to research, news and information for Parkinson's disease, Dementia, the Brain, Depression and Parkinson's with Dystonia. I also post about Fundraising for Parkinson's disease and events. I try to be up-to-date as possible.
I am not responsible for it's contents. I am just a copier of information searched on the computer. Please understand the copies are just that, copies and at times, I am unable to enlarge the wording or keep it uniformed as I wish.
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Saturday, March 14, 2015
Friday, March 13, 2015
- Freezing of gait was significantly improved with DBS at 60 Hz.
- On questionnaires, study participants reported an 80 percent improvement in their ability to swallow with DBS at 60 Hz compared to 130 Hz.
- As viewed on a swallowing test (modified barium swallow study), DBS at 60 Hz reduced the frequency of aspiration (breathing in liquid when swallowing) by 57 percent compared to DBS at 130 Hz.
- For one participant, resting hand tremor worsened with DBS at 60 Hz; this participant returned to 130 Hz DBS after three weeks.
- These improvements lasted as long as DBS was set at 60 Hz.
What Does It Mean?
Researchers assessed the association between the first presentation of prediagnostic features and a subsequent diagnosis of Parkinson's Disease. Those symptoms considered were motor features (tremor, rigidity, balance impairments, neck pain or stiffness, and shoulder pain or stiffness), autonomic features (constipation, hypotension, erectile dysfunction, urinary dysfunction, and dizziness), neuropsychiatric disturbances (memory problems, late-onset anxiety or depression, cognitive decline, and apathy), and additional features (fatigue, insomnia, anosmia, hypersalivation and rapid-eye-movement sleep behaviour disorder).
Apathy, REM sleep disorder, anosmia, hypersalivation, and cognitive decline were excluded because they were infrequently reported. At 10 years before the diagnosis of Parkinson's disease, the prevalence of tremor was an average of 7 times more likely, and constipation was twice as likely in those people who went on to develop Parkinson's disease than in those people who did not have Parkinson 's Disease.
At 5 years before diagnosis, people who went on to develop Parkinson's Disease had a far higher prevalence of tremor (from 7 to 24 times more likely), and also had a higher likelihood (in order or likelihood) of : hypotension, constipation, balance impairments, dizziness, urinary dysfunction, depression, fatigue, anxiety and erectile dysfunction.
At 2 years before Parkinson's disease diagnosis, the prevalence of all studied prediagnostic features except neck pain or stiffness was higher in people who went on to develop Parkinson's Disease.
Reference : Lancet Neurology  14 (1) : 57-64 (A.Schrag, L.Horsfall, K.Walters, A. Noyce, I.Petersen)
Complete abstract : http://www.ncbi.nlm.nih.gov/pubmed/25435387
Thursday, March 12, 2015
A new app that helps Parkinson's Disease patients has been developed with help from researchers at the University of Rochester. The app, called mPower, is only hours old and already has thousands of downloads. It's part of a large research project being conducted at the university. For the first time, the app allows Parkinson's patients to share their symptoms with researchers while also getting to see real-time results themselves. The app is designed to measure dexterity, balance and gait, voice and memory multiple times a day. We can bring about greater collaboration with greater accuracy, but compress the time frame so in that sense it's a very powerful tool," said patient Gary Hilburger. "I really look forward to being able to participate in this study and help out in whatever way I can." "We hope to also understand how the disease changes over the course of time to get better sense of the disease itself and to identify factors, whether disease, diet, exercise or other factors that patients tell us is making their symptoms better or worse," said Dr. Ray Dorsey, M.D., MBA and Professor of Neurology. The app will allow researchers to gain greater insight into the disease. Right now, it is only available for download in the Apple App Store.
Read More at: http://13wham.com//news/features/top-stories/stories/u-r-helps-develop-parkinsons-app-20824.shtml