25th May 2011 - News release
PROSAVIN CLINICAL TRIAL DATA FOR PARKINSON'S DISEASE
Oxford BioMedica, a leading gene therapy company, have announced clinical data from a Phase I/II clinical trial of ProSavin for the treatment of Parkinson’s Disease. They claim : an average improvement in motor function of 43%, a maximum improvement of 61%, an increase in "on" time of 3 hours, and an decrease in "off" time of 4 hours. Two doses have been tested. For more information go to the News release. ProSavin uses Oxford BioMedica's own LentiVector gene delivery technology to deliver the genes for three enzymes that are required for the formation of dopamine. The product is administered locally to the relevant region of the brain in order to increase the brain's own capacity for the formation of dopamine. For more information go to ProSavin.
However, only nine patients have so far been tested, and only for part of the intended duration of the clinical trial. The claim of increased "on" time and decreased "off" time has come only from two patients, and had been entirely self reported by the patients themselves. The claim of an average improvement in motor function of 43%, and a maximum improvement of 61% comes from only three of the patients who have been tested for the least time. It was not the actual average improvement of the patients, which was much less. Those patients tested for the longest actually declined in their improvement as time wore on.
After was running around from doctor to doctor before we finally get rid of her PD ,at age 74 my mother noticed that her handwriting was getting smaller and I was writing faster as well. She also noticed a small tremor in her left hand. The doctor went over her different symptoms and he suspected she either had a small stroke or the beginnings of Parkinson 's disease. After finding a neurologist and some testing she was diagnosed with the beginning stages of Parkinson’s disease. That was 3 years ago. She take Sinimet four times a day to control the symptoms, which include falling, imbalance, gait problems, swallowing difficulties, and slurring of speech,This year, our family doctor started her on multivitamincare. org PD Herbal mixture, 15 weeks into treatment she improved dramatically. At the end of the full treatment course, the disease is totally under control. No case of dementia, hallucination, weakness, muscle pain or tremors.
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