Movement Disorders [2013] 28 (3) : 380-383 (A.M.Wills, S.Eberly, M.Tennis, A.E.Lang, S.Messing, D.Togasaki, C.M.Tanner, C.Kamp, J.F.Chen, D.Oakes, M.P.McDermott, M.A.Schwarzschild)
Caffeine is a naturally occurring adenosine antagonist that is commonly found in coffee, and to a lesser extent in tea, cola drinks, cocoa, and chocolate. Adenosine antagonists reduce or prevent the development of dyskinesia in animal models of L-dopa induced dyskinesia.
Caffeine is a naturally occurring adenosine antagonist that is commonly found in coffee, and to a lesser extent in tea, cola drinks, cocoa, and chocolate. Adenosine antagonists reduce or prevent the development of dyskinesia in animal models of L-dopa induced dyskinesia.
Researchers examined the association between the intake of caffeine and the time taken to develop dyskinesia. Those people who consumed 12 ounces of coffee per day, which is about two cups, reduced their likelihood of developing dyskinesia to 61%. Those people who consumed 4 to 12 ounces of coffee per day, which is less than two cups per day, reduced their likelihood of developing dyskinesia to 73%. The authors suggest tha these results support the possibility that caffeine may reduce the likelihood of developing dyskinesia.
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