Researchers have examined the incidence, progression, and reversion of mild cognitive
impairment in people with Parkinson's Disease (PD-MCI). Mild cognitive impairment (MCI)
is an intermediate stage between the cognitive decline of normal ageing and the more-serious
decline of dementia. It can involve problems with memory (such as forgetting recent events
or repeating the same question), language, thinking, and judgement.
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to : https://www.alzheimers.org.uk/site/scripts/documents_info.php?documentID=120
People with Parkinson's Disease were assessed at diagnosis, after 1 year, after 3 years, and
after 5 years.
At the outset, 20% of them had PD-MCI, after 1 year 30%,
after 3 years 43%, and after 5 years almost half of them
(49%). Few of those people (7%) who did not have mild
cognitive impairment at the outset developed dementia
within the next 5 years. Of those that did have mild cognitive
impairment at the outset, 39% of them developed dementia
within 5 years. Of those that had mild cognitive impairment
after 1 year, 59% of them developed dementia within 5 years.
Over 27% of those people with PD-MCI at the outset actually rid their cognitive impairment
after 5 years, as did 24% of people who had developed cognitive impairment during the first
5 years. However, they were still far more prone to eventually developing dementia.
Although dementia often occurs as Parkinson's Disease worsens, Parkinson's Disease and
dementia are biochemically distinct. Dementia is not actually a dopaminergic symptom.
Reference : Neurology [2017] Jan 20 [Epub ahead of print] (K.F.Pedersen, J.P.Larsen, O.B.
Tysnes, G.Alves) Complete abstract : http://www.ncbi.nlm.nih.gov/pubmed/28108638
http://www.viartis.net/parkinsons.disease/news/170126.pdf
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