Neurology [2013] 80 (2) : 176-180 (Weintraub D, Papay K, Siderowf A)
Although compulsions can often occur in Parkinson's Disease,
Parkinson's Disease does not actually cause compulsions or related problems.
When people with Parkinson's Disease were compared with people who do not have
Parkinson's Disease the frequencies of compulsions were little different :
gambling (1.2% v 0.7%), buying (3% v 2%), sexual behaviour (4.2% v 3.5%), eating
(7% v 10%), punding (prolonged, purposeless, and stereotyped behaviour) (5% v
2%), hobbyism (5% v 12%), walkabout (0.6% v 0.7%), any compulsions (18% v 20%).
The fact that Parkinson's Disease itself does not seem to cause
an increased risk of developing compulsions or related behaviour further
reinforces the reported association between Parkinson's Disease drugs and
causing compulsions. Given that approximately 20% of people with newly diagnosed
Parkinson's Disease report some impulse control or related behaviour symptoms,
long-term follow-up is needed to determine whether such people are at increased
risk for impulse control disorder development once Parkinson's Disease drugs are
initiated.
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