|Alzheimer's disease, which currently affects more than 40 million people, is the most common neurodegenerative disease in elder people.|
Alzheimer's disease, which currently affects more than 40 million people, is the most common neurodegenerative disease in elder people. Early diagnosis is crucial both to treat the disease and to help the development of new medicines, as it hasn't been possible to find a cure so far.
The development of Alzheimer's has been proven to be closely linked to structural changes -related to the gray matter, responsible for processing information- and functional ones -related to the white matter, which connects the different regions of the brain through fibers- in the brain connectivity network, since a significant loss of fibers also causes functional alternations, such as memory loss.
However, diagnosis remains a challenge in spite of the scientific advances made, and to date it hasn't been possible to determine how functional cerebral activity deteriorates the structural one and vice versa, which is a key element to better understand the development of this type of diseases.