WELCOME TO OUR PARKINSON'S PLACE!

I HAVE PARKINSON'S DISEASES AND THOUGHT IT WOULD BE NICE TO HAVE A PLACE WHERE THE CONTENTS OF UPDATED NEWS IS FOUND IN ONE PLACE. THAT IS WHY I BEGAN THIS BLOG.

I COPY NEWS ARTICLES PERTAINING TO RESEARCH, NEWS AND INFORMATION FOR PARKINSON'S DISEASE, DEMENTIA, THE BRAIN, DEPRESSION AND PARKINSON'S WITH DYSTONIA. I ALSO POST ABOUT FUNDRAISING FOR PARKINSON'S DISEASE AND EVENTS. I TRY TO BE UP-TO-DATE AS POSSIBLE.

I AM NOT RESPONSIBLE FOR IT'S CONTENTS. I AM JUST A COPIER OF INFORMATION SEARCHED ON THE COMPUTER. PLEASE UNDERSTAND THE COPIES ARE JUST THAT, COPIES AND AT TIMES, I AM UNABLE TO ENLARGE THE WORDING OR KEEP IT UNIFORMED AS I WISH. IT IS IMPORTANT TO UNDERSTAND I AM A PERSON WITH PARKINSON'S DISEASE. I HAVE NO MEDICAL EDUCATION,

I JUST WANT TO SHARE WITH YOU WHAT I READ ON THE INTERNET. IT IS UP TO YOU TO DECIDE WHETHER TO READ IT AND TALK IT OVER WITH YOUR DOCTOR. I AM JUST THE COPIER OF DOCUMENTS FROM THE COMPUTER. I DO NOT HAVE PROOF OF FACT OR FICTION OF THE ARTICLE. I ALSO TRY TO PLACE A LINK AT THE BOTTOM OF EACH ARTICLE TO SHOW WHERE I RECEIVED THE INFORMATION SO THAT YOU MAY WANT TO VISIT THEIR SITE.

THIS IS FOR YOU TO READ AND TO ALWAYS KEEP AN OPEN MIND.

PLEASE DISCUSS THIS WITH YOUR DOCTOR, SHOULD YOU HAVE ANY QUESTIONS, OR CONCERNS. NEVER DO ANYTHING WITHOUT TALKING TO YOUR DOCTOR FIRST..

I DO NOT MAKE ANY MONEY FROM THIS WEBSITE. I VOLUNTEER MY TIME TO HELP ALL OF US TO BE INFORMED.

I WILL NOT ACCEPT ANY ADVERTISEMENT OR HEALING POWERS, HEALING FROM HERBS AND ETC. UNLESS IT HAS GONE THROUGH TRIALS AND APPROVED BY FDA. IT WILL GO INTO SPAM.

THIS IS A FREE SITE FOR ALL WITH NO ADVERTISEMENTS

THANK YOU FOR VISITING! TOGETHER WE CAN MAKE A DIFFERENCE!

TRANSLATE

Wednesday, April 12, 2017

Revised surgical targeting improves results of deep brain stimulation for depression

April 12, 2017




A study published in Molecular Psychiatry finds that using an advanced imaging technique called Diffusion Tractography Imaging helps researchers find the exact target in patients undergoing Deep Brain Stimulation (DBS) for treatment-resistant depression (TRD).


DBS is a treatment that is widely used in neurological illnesses such as Parkinson's Disease and tremor. Its use in depression is still experimental. The procedure involves placing electrodes in the region of the brain known to affect the circuitry involved in depression. The electrodes are connected to an implantable pulse-generating device in the chest, similar to a pacemaker. The area of the brain that has been most investigated is the subcallosal cingulate white matter area (SCC). 
Up to 10 percent of patients suffering from  go on to develop treatment resistance. Depression tends to become chronic and relapsing, with serious consequences to the patients' quality of life.
In this study, 11 patients with chronic,  had DBS surgery. Using advanced MRI imaging methods, target selection in the SCC was done for each patient using tractography and a specialized 3-D modeling technique that allowed for the precise determination of the exact site for implantation in the brain. 
"We used the images of patients who responded well to DBS in our previous research studies to develop a blueprint or template for use in new subjects. This way, our confidence in finding the exact location for planting the electrode in the subcallosal cingulate was increased," says Patricio Riva-Posse, MD, lead author of the study and assistant professor of psychiatry and behavioral sciences at Emory University School of Medicine. We are very encouraged to see these positive results in the 11 patients who underwent this procedure,"
Results from the study showed eight of the patients (73 percent) responded positively and six were in remission after six months. After one year, nine (82 percent) had improved in their depression scores by more than 50 percent.
By developing this refined blueprint approach to surgery, researchers at Emory say an optimal target can be reliably determined with high precision for each individual patient.
"The outcomes we observed demonstrate progress in the understanding of the networks involved in , and the evolution of this experimental procedure. It is an important step in helping depressed  who have been unresponsive to previous treatments," says Helen S. Mayberg, MD, director of the DBS Depression Research program and professor in the Departments of Psychiatry and Behavioral Sciences, Neurology and Radiology.
Riva-Posse and Mayberg are hopeful this improved method will be considered in the design of future studies evaluating the efficacy of DBS in this difficult-to-treat illness.
More information: P Riva-Posse et al. A connectomic approach for subcallosal cingulate deep brain stimulation surgery: prospective targeting in treatment-resistant depression, Molecular Psychiatry (2017). DOI: 10.1038/MP.2017.59
Journal reference: Molecular Psychiatry

Provided by: Emory University

https://medicalxpress.com/news/2017-04-surgical-results-deep-brain-depression.html

No comments:

Post a Comment